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KMID : 0191120230380480382
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Journal of Korean Medical Science
2023 Volume.38 No. 48 p.382 ~ p.382
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Eosinophilic Granulomatosis With Polyangiitis Following COVID-19 Vaccination: A Case Report
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Hwang Yu-Kyoung
Kwak Hui-Hwan
Yun Jeong-Eun
Kim Sae-Hoon
Chang Yoon-Seok
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Abstract
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The current emergence of the coronavirus disease 2019 (COVID-19) pandemic and the possible side effects of COVID-19 mRNA vaccination remain worrisome. Few cases of vaccination-related side effects, such as vasculitis, have been reported. Eosinophilic granulomatosis with polyangiitis (EGPA), also known as Churg-Strauss syndrome, is a type of vasculitis characterized by the histological richness of eosinophils, asthma, polyneuropathy, sinusitis, and skin or lung involvement. Here, we report the first case of new onset EGPA following COVID-19 vaccination in Korea. A 71-year old woman developed a skin rash and presented with progressive weakness of the upper and lower extremities after the BNT162b2 vaccination (Pfizer-BioNTech). She was diagnosed with EGPA and her symptoms improved after systemic steroid and immunosuppressant therapy. Although it is very rare, clinicians should be aware that EGPA may occur after COVID-19 vaccination.
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KEYWORD
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Churg-Strauss Syndrome, COVID-19, Vaccination
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